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Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide

Epithelial to mesenchymal transition (EMT) is a biological process involved in tissue morphogenesis and disease that causes dramatic changes in cell morphology, migration, proliferation, and gene expression. The retinal pigment epithelium (RPE), which supports the neural retina, can undergo EMT, pro...

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Publicat a:Stem Cell Reports
Autors principals: Boles, Nathan C., Fernandes, Marie, Swigut, Tomasz, Srinivasan, Rajini, Schiff, Lauren, Rada-Iglesias, Alvaro, Wang, Qingjie, Saini, Janmeet S., Kiehl, Thomas, Stern, Jeffrey H., Wysocka, Joanna, Blenkinsop, Timothy A., Temple, Sally
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160390/
https://ncbi.nlm.nih.gov/pubmed/32243845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.03.009
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