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Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest

Neural Crest Cells (NCC) are a transient, embryonic cell population characterized by unusual migratory ability and developmental plasticity. To annotate and characterize cis-regulatory elements utilized by the human NCC we coupled a hESC differentiation model with genome-wide profiling of histone mo...

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Détails bibliographiques
Auteurs principaux: Rada-Iglesias, Alvaro, Bajpai, Ruchi, Prescott, Sara, Brugmann, Samantha, Swigut, Tomek, Wysocka, Joanna
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751405/
https://ncbi.nlm.nih.gov/pubmed/22981823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.07.006
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