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XPO5 promotes primary miRNA processing independently of RanGTP

XPO5 mediates nuclear export of miRNA precursors in a RanGTP-dependent manner. However, XPO5-associated RNA species have not been determined globally and it is unclear whether XPO5 has any additional functions other than nuclear export. Here we show XPO5 pervasively binds to double-stranded RNA regi...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wang, Jingjing, Lee, Jerome E., Riemondy, Kent, Yu, Yang, Marquez, Steven M., Lai, Eric C., Yi, Rui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160132/
https://ncbi.nlm.nih.gov/pubmed/32296071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15598-x
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