Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

The involvement of host immunity in the gut microbiota-mediated colonization resistance to Clostridioides difficile infection (CDI) is incompletely understood. Here, we show that interleukin (IL)-22, induced by colonization of the gut microbiota, is crucial for the prevention of CDI in human microbi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Med
Main Authors: Nagao-Kitamoto, Hiroko, Leslie, Jhansi L., Kitamoto, Sho, Jin, Chunsheng, Thomsson, Kristina A., Gillilland, Merritt G., Kuffa, Peter, Goto, Yoshiyuki, Jenq, Robert R., Ishii, Chiharu, Hirayama, Akiyoshi, Seekatz, Anna M., Martens, Eric C., Eaton, Kathryn A., Kao, John Y., Fukuda, Shinji, Higgins, Peter D. R., Karlsson, Niclas G., Young, Vincent B., Kamada, Nobuhiko
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160049/
https://ncbi.nlm.nih.gov/pubmed/32066975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0764-0
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki