Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

The involvement of host immunity in the gut microbiota-mediated colonization resistance to Clostridioides difficile infection (CDI) is incompletely understood. Here, we show that interleukin (IL)-22, induced by colonization of the gut microbiota, is crucial for the prevention of CDI in human microbi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Med
Hlavní autoři: Nagao-Kitamoto, Hiroko, Leslie, Jhansi L., Kitamoto, Sho, Jin, Chunsheng, Thomsson, Kristina A., Gillilland, Merritt G., Kuffa, Peter, Goto, Yoshiyuki, Jenq, Robert R., Ishii, Chiharu, Hirayama, Akiyoshi, Seekatz, Anna M., Martens, Eric C., Eaton, Kathryn A., Kao, John Y., Fukuda, Shinji, Higgins, Peter D. R., Karlsson, Niclas G., Young, Vincent B., Kamada, Nobuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160049/
https://ncbi.nlm.nih.gov/pubmed/32066975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0764-0
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky