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Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells

Monocytes play a crucial role in antimicrobial host defence, but the mechanisms by which they protect the host during intestinal infection remains poorly understood. Here we show that depletion of CCR2(+) monocytes results in impaired clearance of the intestinal pathogen Citrobacter rodentium. After...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Seo, Sang-Uk, Kuffa, Peter, Kitamoto, Sho, Nagao-Kitamoto, Hiroko, Rousseau, Jenna, Kim, Yun-Gi, Núñez, Gabriel, Kamada, Nobuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536571/
https://ncbi.nlm.nih.gov/pubmed/26269452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9010
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