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Evaluation of Top-Down Mass Spectrometry and Ion-Mobility Spectroscopy as a Means of Mapping Protein-Binding Motifs within Heparin Chains
Identifying structural elements within heparin (as well as other glycosaminoglycan) chains that enable their interaction with a specific client protein remains a challenging task due to the high degree of both intra- and inter-chain heterogeneity exhibited by this polysaccharide. The new experimenta...
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| Pubblicato in: | Analyst |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7160044/ https://ncbi.nlm.nih.gov/pubmed/32150181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0an00097c |
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