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A Graphene‐Based Platform for the Assay of Duplex‐DNA Unwinding by Helicase

Time to unwind: Graphene oxide (GO) enables the quantitative measurement of helicase‐dependent double‐stranded DNA (dsDNA) unwinding activity in real time. GO selectively binds to unwound fluorescent‐dye‐labeled single‐stranded DNA and quenches its fluorescence (see picture). The helicase activity i...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Jang, Hongje, Kim, Young‐Kwan, Kwon, Hyun‐Mi, Yeo, Woon‐Seok, Kim, Dong‐Eun, Min, Dal‐Hee
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159720/
https://ncbi.nlm.nih.gov/pubmed/20818755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201001332
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