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A Graphene‐Based Platform for the Assay of Duplex‐DNA Unwinding by Helicase

Time to unwind: Graphene oxide (GO) enables the quantitative measurement of helicase‐dependent double‐stranded DNA (dsDNA) unwinding activity in real time. GO selectively binds to unwound fluorescent‐dye‐labeled single‐stranded DNA and quenches its fluorescence (see picture). The helicase activity i...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Jang, Hongje, Kim, Young‐Kwan, Kwon, Hyun‐Mi, Yeo, Woon‐Seok, Kim, Dong‐Eun, Min, Dal‐Hee
Format: Artigo
Sprog:Inglês
Udgivet: WILEY‐VCH Verlag 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159720/
https://ncbi.nlm.nih.gov/pubmed/20818755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201001332
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