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Molecular mimicry and multiple sclerosis: Degenerate T‐cell recognition and the induction of autoimmunity

Various mechanisms have been proposed for the initiation of autoimmune responses by autoreactive T‐cell clones. One of these, the molecular mimicry hypothesis, postulates that myelin‐reactive T‐cell clones are activated by foreign antigens. Until recently, sequence homology between self‐ and foreign...

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Bibliografische gegevens
Gepubliceerd in:Ann Neurol
Hoofdauteurs: Gran, Bruno, Hemmer, Bernhard, Vergelli, Marco, McFarland, Henry F., Martin, Roland
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Inc. 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159663/
https://ncbi.nlm.nih.gov/pubmed/10319877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1531-8249(199905)45:5<559::AID-ANA3>3.0.CO;2-Q
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