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Molecular mimicry and multiple sclerosis: Degenerate T‐cell recognition and the induction of autoimmunity

Various mechanisms have been proposed for the initiation of autoimmune responses by autoreactive T‐cell clones. One of these, the molecular mimicry hypothesis, postulates that myelin‐reactive T‐cell clones are activated by foreign antigens. Until recently, sequence homology between self‐ and foreign...

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Detalles Bibliográficos
Publicado en:Ann Neurol
Main Authors: Gran, Bruno, Hemmer, Bernhard, Vergelli, Marco, McFarland, Henry F., Martin, Roland
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159663/
https://ncbi.nlm.nih.gov/pubmed/10319877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1531-8249(199905)45:5<559::AID-ANA3>3.0.CO;2-Q
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