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Molecular mimicry and multiple sclerosis: Degenerate T‐cell recognition and the induction of autoimmunity

Various mechanisms have been proposed for the initiation of autoimmune responses by autoreactive T‐cell clones. One of these, the molecular mimicry hypothesis, postulates that myelin‐reactive T‐cell clones are activated by foreign antigens. Until recently, sequence homology between self‐ and foreign...

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Bibliografski detalji
Izdano u:Ann Neurol
Glavni autori: Gran, Bruno, Hemmer, Bernhard, Vergelli, Marco, McFarland, Henry F., Martin, Roland
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159663/
https://ncbi.nlm.nih.gov/pubmed/10319877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1531-8249(199905)45:5<559::AID-ANA3>3.0.CO;2-Q
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