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Molecular mimicry and multiple sclerosis: Degenerate T‐cell recognition and the induction of autoimmunity

Various mechanisms have been proposed for the initiation of autoimmune responses by autoreactive T‐cell clones. One of these, the molecular mimicry hypothesis, postulates that myelin‐reactive T‐cell clones are activated by foreign antigens. Until recently, sequence homology between self‐ and foreign...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Ann Neurol
Hauptverfasser: Gran, Bruno, Hemmer, Bernhard, Vergelli, Marco, McFarland, Henry F., Martin, Roland
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159663/
https://ncbi.nlm.nih.gov/pubmed/10319877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1531-8249(199905)45:5<559::AID-ANA3>3.0.CO;2-Q
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