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Characterization and Inhibition of the Main Protease of Severe Acute Respiratory Syndrome Coronavirus

The main protease of SARS‐associated coronavirus (SARS‐CoV), also called 3C‐like protease (3CL(pro)), is vital for the viral replication. It cleaves the replicase polyproteins at 11 sites and is a promising drug target. Several groups of inhibitors have been identified through high‐throughput screen...

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Bibliografske podrobnosti
izdano v:ChemBioEng Reviews
Main Authors: Kuo, Chih‐Jung, Liang, Po‐Huang
Format: Artigo
Jezik:Inglês
Izdano: WILEY‐VCH Verlag 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159133/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cben.201400031
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