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Characterization and Inhibition of the Main Protease of Severe Acute Respiratory Syndrome Coronavirus
The main protease of SARS‐associated coronavirus (SARS‐CoV), also called 3C‐like protease (3CL(pro)), is vital for the viral replication. It cleaves the replicase polyproteins at 11 sites and is a promising drug target. Several groups of inhibitors have been identified through high‐throughput screen...
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| Publié dans: | ChemBioEng Reviews |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY‐VCH Verlag
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7159133/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cben.201400031 |
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