Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus

The papain-like protease of severe acute respiratory syndrome coronavirus (PLpro) (EC 3.4.22.46) is essential for the viral life cycle and therefore represents an important antiviral target. We have identified 6MP and 6TG as reversible and slow-binding inhibitors of SARS-CoV PLpro, which is the firs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Pharmacol
Egile Nagusiak: Chou, Chi-Yuan, Chien, Chia-Hui, Han, Yu-San, Prebanda, Mojca Trstenjak, Hsieh, Hsing-Pang, Turk, Boris, Chang, Gu-Gang, Chen, Xin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Inc. 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092826/
https://ncbi.nlm.nih.gov/pubmed/18313035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.01.005
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak