ロード中...

Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus

The papain-like protease of severe acute respiratory syndrome coronavirus (PLpro) (EC 3.4.22.46) is essential for the viral life cycle and therefore represents an important antiviral target. We have identified 6MP and 6TG as reversible and slow-binding inhibitors of SARS-CoV PLpro, which is the firs...

詳細記述

保存先:
書誌詳細
出版年:Biochem Pharmacol
主要な著者: Chou, Chi-Yuan, Chien, Chia-Hui, Han, Yu-San, Prebanda, Mojca Trstenjak, Hsieh, Hsing-Pang, Turk, Boris, Chang, Gu-Gang, Chen, Xin
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Inc. 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092826/
https://ncbi.nlm.nih.gov/pubmed/18313035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.01.005
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!