Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth

The discovery of potent and broadly protective influenza virus epitopes could lead to improved vaccines that are resistant to antigenic drift. Here, we describe human antibody C585, isolated from a vaccinee with remarkable serological breadth as measured by hemagglutinin inhibition (HAI). C585 binds...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Qiu, Yu, Stegalkina, Svetlana, Zhang, Jianxin, Boudanova, Ekaterina, Park, Anna, Zhou, Yanfeng, Prabakaran, Ponraj, Pougatcheva, Svetlana, Ustyugova, Irina V., Vogel, Thorsten U., Mundle, Sophia T., Oomen, Ray, Delagrave, Simon, Ross, Ted M., Kleanthous, Harry, Qiu, Huawei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158729/
https://ncbi.nlm.nih.gov/pubmed/31826999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01035-19
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge