High-Purity Preparation of HSV-2 Vaccine Candidate ACAM529 Is Immunogenic and Efficacious In Vivo

Genital herpes is a sexually transmitted infection (STI) caused by herpes simplex virus 2 (HSV-2) and to a lesser extent herpes simplex virus 1 (HSV-1). Infection by HSV-2 is life-long and is associated with significant cost to healthcare systems and social stigma despite the highly prevalent nature...

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Main Authors: Mundle, Sophia T., Hernandez, Hector, Hamberger, John, Catalan, John, Zhou, Changhong, Stegalkina, Svetlana, Tiffany, Andrea, Kleanthous, Harry, Delagrave, Simon, Anderson, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582571/
https://ncbi.nlm.nih.gov/pubmed/23468943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057224
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