Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains

Most humans have pre-existing immunity to influenza viruses. In this study, volunteers (ages of 18–85 years) were vaccinated with split, inactivated Fluzone(™) influenza vaccine in four consecutive influenza seasons from 2013 to 2016 seasons. The impact of repeated vaccination on breadth and durabil...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nuñez, Ivette A., Carlock, Michael A., Allen, James D., Owino, Simon O., Moehling, Krissy K., Nowalk, Patricia, Susick, Michael, Diagle, Kensington, Sweeney, Kristen, Mundle, Sophia, Vogel, Thorsten U., Delagrave, Simon, Ramgopal, Moti, Zimmerman, Richard K., Kleanthous, Harry, Ross, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665503/
https://ncbi.nlm.nih.gov/pubmed/29091724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185666
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