Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice

BACKGROUND: Progressive β-cell dysfunction, a major characteristic of type 2 diabetes (T2D), is closely related to the infiltration of inflammatory macrophages within islets. Mesenchymal stem cells (MSCs) have been identified to alleviate β-cell dysfunction by modulating macrophage phenotype in T2D,...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Xue, Jing, Cheng, Yu, Hao, Haojie, Gao, Jieqing, Yin, Yaqi, Yu, Songyan, Zou, Junyan, Liu, Jiejie, Zhang, Qi, Mu, Yiming
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157805/
https://ncbi.nlm.nih.gov/pubmed/32322278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4689798
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