Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice

Progressive pancreatic β-cell dysfunction is recognized as a fundamental pathology of type 2 diabetes (T2D). Recently, mesenchymal stem cells (MSCs) have been identified in protection of islets function in T2D individuals. However, the underlying mechanisms remain elusive. It is widely accepted that...

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Pubblicato in:Cell Death Dis
Autori principali: Yin, Yaqi, Hao, Haojie, Cheng, Yu, Zang, Li, Liu, Jiejie, Gao, Jieqing, Xue, Jing, Xie, Zongyan, Zhang, Qi, Han, Weidong, Mu, Yiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037817/
https://ncbi.nlm.nih.gov/pubmed/29988034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0801-9
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