Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic mice

BACKGROUND: Mesenchymal stem cells (MSCs) have emerged as a promising therapy for type 2 diabetes (T2D). Mechanistic researches demonstrate that the anti-diabetic effect of MSCs is partially mediated by eliciting macrophages into an anti-inflammatory phenotype thus alleviating insulin resistance. Ho...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Gao, Jieqing, Cheng, Yu, Hao, Haojie, Yin, Yaqi, Xue, Jing, Zhang, Qi, Li, Lin, Liu, Jiejie, Xie, Zongyan, Yu, Songyan, Li, Bing, Han, Weidong, Mu, Yiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700792/
https://ncbi.nlm.nih.gov/pubmed/31426846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1338-2
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