Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance by suppressing NLRP3 inflammasome-mediated inflammation in type 2 diabetes rats

BACKGROUND: Insulin resistance is one of the most common and important pathological features of type 2 diabetes (T2D). Recently, insulin resistance is increasingly considered to be associated with systemic chronic inflammation. Elevated levels of tumor necrosis factor (TNF)-α and interleukin (IL)-1β...

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Publicat a:Stem Cell Res Ther
Autors principals: Sun, Xiaoya, Hao, Haojie, Han, Qingwang, Song, Xiaoyan, Liu, Jiejie, Dong, Liang, Han, Weidong, Mu, Yiming
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667486/
https://ncbi.nlm.nih.gov/pubmed/29096724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0668-1
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