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Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

In this study, radiotherapy was combined with the gene electrotransfer (GET) of plasmid encoding shRNA against melanoma cell adhesion molecule (pMCAM) with dual action, which was a vascular-targeted effect mediated by the silencing of MCAM and an immunological effect mediated by the presence of plas...

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Библиографические подробности
Опубликовано в: :Vaccines (Basel)
Главные авторы: Kranjc Brezar, Simona, Mrak, Valter, Bosnjak, Masa, Savarin, Monika, Sersa, Gregor, Cemazar, Maja
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157247/
https://ncbi.nlm.nih.gov/pubmed/32204304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010135
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