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Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

In this study, radiotherapy was combined with the gene electrotransfer (GET) of plasmid encoding shRNA against melanoma cell adhesion molecule (pMCAM) with dual action, which was a vascular-targeted effect mediated by the silencing of MCAM and an immunological effect mediated by the presence of plas...

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Detalles Bibliográficos
Publicado en:Vaccines (Basel)
Main Authors: Kranjc Brezar, Simona, Mrak, Valter, Bosnjak, Masa, Savarin, Monika, Sersa, Gregor, Cemazar, Maja
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157247/
https://ncbi.nlm.nih.gov/pubmed/32204304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010135
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