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Radiosensitizing effect of intratumoral interleukin-12 gene electrotransfer in murine sarcoma

BACKGROUND: Interleukin-12 (IL-12) based radiosensitization is an effective way of tumor treatment. Local cytokine production, without systemic shedding, might provide clinical benefit in radiation treatment of sarcomas. Therefore, the aim was to stimulate intratumoral IL-12 production by gene elect...

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Detalhes bibliográficos
Main Authors: Sedlar, Ales, Kranjc, Simona, Dolinsek, Tanja, Cemazar, Maja, Coer, Andrej, Sersa, Gregor
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562515/
https://ncbi.nlm.nih.gov/pubmed/23360213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-38
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