Multiple Delivery of siRNA against Endoglin into Murine Mammary Adenocarcinoma Prevents Angiogenesis and Delays Tumor Growth

Endoglin is a transforming growth factor-β (TGF- β) co-receptor that participates in the activation of a signaling pathway that mediates endothelial cell proliferation and migration in angiogenic tumor vasculature. Therefore, silencing of endoglin expression is an attractive approach for antiangioge...

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Detalhes bibliográficos
Main Authors: Dolinsek, Tanja, Markelc, Bostjan, Sersa, Gregor, Coer, Andrej, Stimac, Monika, Lavrencak, Jaka, Brozic, Andreja, Kranjc, Simona, Cemazar, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589348/
https://ncbi.nlm.nih.gov/pubmed/23593103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058723
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