Loading...

Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

In this study, radiotherapy was combined with the gene electrotransfer (GET) of plasmid encoding shRNA against melanoma cell adhesion molecule (pMCAM) with dual action, which was a vascular-targeted effect mediated by the silencing of MCAM and an immunological effect mediated by the presence of plas...

Full description

Saved in:
Bibliographic Details
Published in:Vaccines (Basel)
Main Authors: Kranjc Brezar, Simona, Mrak, Valter, Bosnjak, Masa, Savarin, Monika, Sersa, Gregor, Cemazar, Maja
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157247/
https://ncbi.nlm.nih.gov/pubmed/32204304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010135
Tags: Add Tag
No Tags, Be the first to tag this record!