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Understanding the 26S proteasome molecular machine from a structural and conformational dynamics perspective

The 26S proteasome is the essential compartmental protease in eukaryotic cells required for the ubiquitin-dependent clearance of damaged polypeptides and obsolete regulatory proteins. Recently, a combination of high-resolution structural, biochemical, and biophysical studies has provided critical ne...

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Foilsithe in:Curr Opin Struct Biol
Main Authors: Greene, Eric R, Dong, Ken C, Martin, Andreas
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156321/
https://ncbi.nlm.nih.gov/pubmed/31783300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.10.004
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