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Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome

Substrates are targeted for proteasomal degradation through the attachment of ubiquitin chains that need to be removed by proteasomal deubiquitinases prior to substrate processing. In budding yeast, the deubiquitinase Ubp6 trims ubiquitin chains and affects substrate processing by the proteasome, bu...

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Bibliografske podrobnosti
izdano v:Nat Struct Mol Biol
Main Authors: Bashore, Charlene, Dambacher, Corey M., Goodall, Ellen A., Matyskiela, Mary E., Lander, Gabriel C., Martin, Andreas
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560640/
https://ncbi.nlm.nih.gov/pubmed/26301997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3075
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