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Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome

Substrates are targeted for proteasomal degradation through the attachment of ubiquitin chains that need to be removed by proteasomal deubiquitinases prior to substrate processing. In budding yeast, the deubiquitinase Ubp6 trims ubiquitin chains and affects substrate processing by the proteasome, bu...

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Pubblicato in:Nat Struct Mol Biol
Autori principali: Bashore, Charlene, Dambacher, Corey M., Goodall, Ellen A., Matyskiela, Mary E., Lander, Gabriel C., Martin, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560640/
https://ncbi.nlm.nih.gov/pubmed/26301997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3075
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