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A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research

Increasing evidence suggests that the process of alpha‐synuclein (α‐syn) aggregation from monomers into amyloid fibrils and Lewy bodies, via oligomeric intermediates plays an essential role in the pathogenesis of different synucleinopathies, including Parkinson's disease (PD), multiple system a...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Kumar, Senthil T., Donzelli, Sonia, Chiki, Anass, Syed, Muhammed Muazzam Kamil, Lashuel, Hilal A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155127/
https://ncbi.nlm.nih.gov/pubmed/31925956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14955
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