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Heparin inhibits proinflammatory and promotes anti-inflammatory macrophage polarization under hyperglycemic stress

Monocytes are rapidly recruited to sites of diabetic complications and differentiate into macrophages. Previously, we showed that rat kidney mesangial cells dividing during hyperglycemic stress abnormally synthesize hyaluronan (HA) in intracellular compartments. This initiates a stress response, res...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Abbadi, Amina, Loftis, Jacqueline, Wang, Aimin, Yu, Minjia, Wang, Yan, Shakya, Sajina, Li, Xiaoxia, Maytin, Edward, Hascall, Vincent
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152777/
https://ncbi.nlm.nih.gov/pubmed/32107314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012419
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