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Heparin affects cytosolic glucose responses of hyperglycemic dividing mesangial cells

Mesangial expansion underlies diabetic nephropathy, leading to sclerosis and renal failure. The glycosaminoglycan heparin inhibits mesangial cell growth, but the molecular mechanism is unclear. Here, rat mesangial cells (RMCs) were growth-arrested in the G(0)/G(1) phase of cell division, stimulated...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Wang, Andrew Jun, Ren, Juan, Abbadi, Amina, Wang, Aimin, Hascall, Vincent C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484118/
https://ncbi.nlm.nih.gov/pubmed/30723159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007395
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