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Heparin Prevents Intracellular Hyaluronan Synthesis and Autophagy Responses in Hyperglycemic Dividing Mesangial Cells and Activates Synthesis of an Extensive Extracellular Monocyte-adhesive Hyaluronan Matrix after Completing Cell Division

Growth-arrested rat mesangial cells (RMCs) at a G(0)/G(1) interphase stimulated to divide in hyperglycemic medium initiate intracellular hyaluronan synthesis that induces autophagy/cyclin D3-induced formation of a monocyte-adhesive extracellular hyaluronan matrix after completing cell division. This...

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Detalhes bibliográficos
Main Authors: Wang, Aimin, Ren, Juan, Wang, Christina P., Hascall, Vincent C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979390/
https://ncbi.nlm.nih.gov/pubmed/24482224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541441
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