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Heparin inhibits proinflammatory and promotes anti-inflammatory macrophage polarization under hyperglycemic stress
Monocytes are rapidly recruited to sites of diabetic complications and differentiate into macrophages. Previously, we showed that rat kidney mesangial cells dividing during hyperglycemic stress abnormally synthesize hyaluronan (HA) in intracellular compartments. This initiates a stress response, res...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7152777/ https://ncbi.nlm.nih.gov/pubmed/32107314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012419 |
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