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Heparin inhibits proinflammatory and promotes anti-inflammatory macrophage polarization under hyperglycemic stress

Monocytes are rapidly recruited to sites of diabetic complications and differentiate into macrophages. Previously, we showed that rat kidney mesangial cells dividing during hyperglycemic stress abnormally synthesize hyaluronan (HA) in intracellular compartments. This initiates a stress response, res...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Abbadi, Amina, Loftis, Jacqueline, Wang, Aimin, Yu, Minjia, Wang, Yan, Shakya, Sajina, Li, Xiaoxia, Maytin, Edward, Hascall, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152777/
https://ncbi.nlm.nih.gov/pubmed/32107314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012419
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