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Biochemical characterization of acyl activating enzymes for side chain moieties of Taxol and its analogs
Taxol (paclitaxel) is a very widely used anticancer drug, but its commercial sources mainly consist of stripped bark or suspension cultures of members of the plant genus Taxus. Taxol accumulates as part of a complex mixture of chemical analogs, termed taxoids, which complicates its production in pur...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7152758/ https://ncbi.nlm.nih.gov/pubmed/32086380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012663 |
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