Short-chain analogs of luteinizing hormone-releasing hormone containing cytotoxic moieties.

Five hexapeptide and heptapeptide analogs of luteinizing hormone-releasing hormone (LH-RH) were synthesized for use as carriers for cytotoxic compounds. These short analogs were expected to enhance target selectivity of the antineoplastic agents linked to them. Native LH-RH-(3-9) and LH-RH-(4-9) con...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Janáky, T, Juhász, A, Rékási, Z, Serfözö, P, Pinski, J, Bokser, L, Srkalovic, G, Milovanovic, S, Redding, T W, Halmos, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50306/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1332035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.21.10203
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