Cytotoxic analogs of luteinizing hormone-releasing hormone containing doxorubicin or 2-pyrrolinodoxorubicin, a derivative 500-1000 times more potent.

Eitemau Tebyg

• High yield conversion of doxorubicin to 2-pyrrolinodoxorubicin, an analog 500-1000 times more potent: structure-activity relationship of daunosamine-modified derivatives of doxorubicin.
  gan: Nagy, A, et al.
  Cyhoeddwyd: (1996)
• Design, synthesis, and in vitro evaluation of cytotoxic analogs of bombesin-like peptides containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin
  gan: Nagy, Attila, et al.
  Cyhoeddwyd: (1997)
• Synthesis and biological evaluation of cytotoxic analogs of somatostatin containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin
  gan: Nagy, Attila, et al.
  Cyhoeddwyd: (1998)
• Inhibition of growth of OV-1063 human epithelial ovarian cancer xenografts in nude mice by treatment with luteinizing hormone-releasing hormone antagonist SB-75.
  gan: Yano, T, et al.
  Cyhoeddwyd: (1994)
• Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers
  gan: Szepeshazi, K, et al.
  Cyhoeddwyd: (2000)