Short-chain analogs of luteinizing hormone-releasing hormone containing cytotoxic moieties.

Five hexapeptide and heptapeptide analogs of luteinizing hormone-releasing hormone (LH-RH) were synthesized for use as carriers for cytotoxic compounds. These short analogs were expected to enhance target selectivity of the antineoplastic agents linked to them. Native LH-RH-(3-9) and LH-RH-(4-9) con...

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Autors principals: Janáky, T, Juhász, A, Rékási, Z, Serfözö, P, Pinski, J, Bokser, L, Srkalovic, G, Milovanovic, S, Redding, T W, Halmos, G
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC50306/
https://ncbi.nlm.nih.gov/pubmed/1332035
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