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The final acylation step in Taxol biosynthesis: Cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus

The formation of several acyl groups and an amide group of Taxol is catalyzed by regioselective CoA thioester-dependent acyltransferases. Several full-length acyltransferase sequences, obtained from a cDNA library constructed from mRNA isolated from Taxus cuspidata cells induced for Taxol production...

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Bibliographic Details
Main Authors: Walker, Kevin, Long, Robert, Croteau, Rodney
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC123112/
https://ncbi.nlm.nih.gov/pubmed/12089320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082115799
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