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The final acylation step in Taxol biosynthesis: Cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus

The formation of several acyl groups and an amide group of Taxol is catalyzed by regioselective CoA thioester-dependent acyltransferases. Several full-length acyltransferase sequences, obtained from a cDNA library constructed from mRNA isolated from Taxus cuspidata cells induced for Taxol production...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Walker, Kevin, Long, Robert, Croteau, Rodney
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123112/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12089320/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082115799
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