Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging microscopy (FLIM) data

The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local DNA template access, and through continuous dynamic rearrangements, regulates genome function [1]. However, given that nucleosome packaging occurs on a spatial scale well below the diffraction limit, r...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Data Brief
Päätekijät: Liang, Zhen, Lou, Jieqiong, Scipioni, Lorenzo, Gratton, Enrico, Hinde, Elizabeth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
Aiheet:
Biochemistry, Genetics and Molecular Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152662/
https://ncbi.nlm.nih.gov/pubmed/32300614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2020.105401
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