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Mutational Load and the Functional Fraction of the Human Genome

The fraction of the human genome that is functional is a question of both evolutionary and practical importance. Studies of sequence divergence have suggested that the functional fraction of the human genome is likely to be no more than ∼15%. In contrast, the ENCODE project, a systematic effort to m...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Galeota-Sprung, Benjamin, Sniegowski, Paul, Ewens, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7151545/
https://ncbi.nlm.nih.gov/pubmed/32108234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evaa040
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