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What fraction of the human genome is functional?
Many evolutionary studies over the past decade have estimated α(sel), the proportion of all nucleotides in the human genome that are subject to purifying selection because of their biological function. Most of these studies have estimated the nucleotide substitution rates from genome sequence alignm...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205562/ https://ncbi.nlm.nih.gov/pubmed/21875934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.116814.110 |
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