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8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage

Ten years on from the finishing of the human reference genome sequence, it remains unclear what fraction of the human genome confers function, where this sequence resides, and how much is shared with other mammalian species. When addressing these questions, functional sequence has often been equated...

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Detalhes bibliográficos
Main Authors: Rands, Chris M., Meader, Stephen, Ponting, Chris P., Lunter, Gerton
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109858/
https://ncbi.nlm.nih.gov/pubmed/25057982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004525
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