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8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage

Ten years on from the finishing of the human reference genome sequence, it remains unclear what fraction of the human genome confers function, where this sequence resides, and how much is shared with other mammalian species. When addressing these questions, functional sequence has often been equated...

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Autors principals: Rands, Chris M., Meader, Stephen, Ponting, Chris P., Lunter, Gerton
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109858/
https://ncbi.nlm.nih.gov/pubmed/25057982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004525
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