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Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors

Peptides derived from the C-terminal heptad repeat (CHR) region of HIV-1 gp41 is potent viral membrane fusion inhibitors, such as the first clinically approved peptide drug T20 and a group of newly-designed peptides. The resistance profiles of various HIV-1 fusion inhibitors were previously characte...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Yu, Danwei, Su, Yang, Ding, Xiaohui, Zhu, Yuanmei, Qin, Bo, Chong, Huihui, Cui, Sheng, He, Yuxian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150849/
https://ncbi.nlm.nih.gov/pubmed/32197300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12030326
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