Mechanism of HIV-1 Resistance to an Electronically Constrained α-Helical Peptide Membrane Fusion Inhibitor

SC29EK is an electronically constrained α-helical peptide HIV-1 fusion inhibitor that is highly effective against both wild-type and enfuvirtide (T20)-resistant viruses. In this study, we focused on investigating the mechanism of HIV-1 resistance to SC29EK by two approaches. First, SC29EK-escaping H...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Wu, Xiyuan, Liu, Zixuan, Ding, Xiaohui, Yu, Danwei, Wei, Huamian, Qin, Bo, Zhu, Yuanmei, Chong, Huihui, Cui, Sheng, He, Yuxian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972894/
https://ncbi.nlm.nih.gov/pubmed/29321334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02044-17
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