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Structural and Functional Characterization of Membrane Fusion Inhibitors with Extremely Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus

T-20 (enfuvirtide) is the only membrane fusion inhibitor available for the treatment of viral infection; however, it has low anti-human immunodeficiency virus (anti-HIV) activity and a low genetic barrier for drug resistance. We recently reported that T-20 sequence-based lipopeptides possess extreme...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Chong, Huihui, Zhu, Yuanmei, Yu, Danwei, He, Yuxian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158425/
https://ncbi.nlm.nih.gov/pubmed/30089693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01088-18
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